Process for the preparation of diamine intermediates useful in t

Details Process for the preparation of diamine intermediates useful in t Process for the preparation of diamine intermediates useful in t

1994-06-30

1996-09-24

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549450, 549265, 549296, C07C23506

Patent

active

055592520

ABSTRACT:
The present invention provides a process for the preparation of compounds of formula (V) below, and analogs thereof, which are useful as intermediates for the synthesis of HIV protease inhibitors, including cyclic ureas. ##STR1##

REFERENCES:
patent: 5294720 (1994-03-01), Jadhav et al.
W. R. Baker and S. L. Condon, J. Org. Chem., 1993, 58, 3277-3284.
D. J. Kempf et al., J. Org. Chem., 1992, 57, 5692-5700.
Lam et al., Science, 1994, 263, 380-384.
B. Chenera, J. C. Boehm & G. B. Dreyer, Bioorganic & Med. Chem. Lett., 1991, 1, 219-222.
P. K. Jadhav & F. J. Woerner, Bioorganic & Med. Chem. Lett., 1992, 2, 353-356.
A. K. Ghosh, S. P. McKee & W. J. Thompson, Tetrahedron Lett., 1991, 32, 5729-5732.
G. B. Dreyer et al., Biochemistry 1993, 32, 937-947.

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