Process for the preparation of dialkali metal cromoglycates

Details Process for the preparation of dialkali metal cromoglycates Process for the preparation of dialkali metal cromoglycates

1994-07-07

1996-04-16

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31124

Patent

active

055084516

ABSTRACT:
A process for preparing a dialkali metal cromoglycate which comprises (1) condensing a hydroxy substituted ketone with a condensing agent in the presence of a base material and an organic solvent; (2) subjecting the condensed material to ring-closure conditions, first in the presence of an alkali metal alkoxide and a suitable organic solvent, then followed by the addition of substantially dry mineral acid and a suitable organic solvent; and (3) hydrolyzing the ring-closed material in the presence of a base material and a suitable organic solvent to form said cromoglycate.

REFERENCES:
patent: 3419578 (1968-12-01), Fitzmaurice et al.

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