Process for the preparation of D-ribavirin

Details Process for the preparation of D-ribavirin Process for the preparation of D-ribavirin

2007-10-23

2007-10-23

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S055300, C536S124000

Reexamination Certificate

active

10485335

ABSTRACT:
A process for the preparation of ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid. Said process comprises:a) the reaction of a triazole of the formula with a protected ribofuranose of the formulab) the removal of the Pg groups and, optionally, the conversion into a carboxyamide group of the R2group of the compound obtained of the formula DD/mac—01.07.02.

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patent: 55160793 (1980-12-01), None
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