Process for the preparation of cyclopropylglycine

Details Process for the preparation of cyclopropylglycine Process for the preparation of cyclopropylglycine

1999-11-16

2000-08-15

O'Sullivan, Peter

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

558315, 558390, 562506, 564271, 564276, C07C25300, C07C25106, C07C22936, C07C22928, C07C22718

Patent

active

061039292

ABSTRACT:
Disclosed is a process for the preparation of cyclopropylglycine by a 5-step process wherein cyclopropanecarboxaldehyde is reacted with an .alpha.-aminoalkylaromatic compound to obtain an imine which is reacted with a cyanide to produce an aminonitrile compound; the aminonitrile compound is hydrolyzed to the corresponding aminocarboxylic acid and finally the arylalkyl residue is removed from the amino group by hydrogenolysis.

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