Process for the preparation of cyanomethyl carboxylates

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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C07C12000

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active

046250450

ABSTRACT:
A one step process for the preparation of certain cyanomethyl carboxylates is disclosed which comprises reacting an appropriate acyl compound with a water soluble metal cyanide such as sodium cyanide or potassium cyanide and an aldehyde such as formaldehyde, acetaldehyde, or benzaldehyde. Also disclosed is a method for inhibiting bacteria by contacting said bacteria or habitat thereof with an effective amount of an antibacterial cyanomethyl carboxylate.

REFERENCES:
patent: 3758526 (1973-09-01), Fujita et al.
patent: 3873591 (1975-03-01), Smith et al.
patent: 4115430 (1978-09-01), Rohr
patent: 4123451 (1978-10-01), Sheldon et al.
patent: 4252814 (1981-02-01), Wepplo et al.
Babaeva et al., Chemical Abstracts, vol. 86, 16157t (1977).
Buyle, Chemical Abstracts, vol. 62, 5157h (1965).
Grudzinski, Chemical Abstracts, vol. 59, 7476 (1963).

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