Process for the preparation of crystalline N-formimidoyl...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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07078534

ABSTRACT:
The present invention relates to a cost effective and commercially viable process for the preparation of crystalline N-formimidoyl thienamycin monohydrate (Imipenem monohydrate) of Formula I.

REFERENCES:
patent: 4194047 (1980-03-01), Christensen et al.
patent: 4260543 (1981-04-01), Miller
patent: 5245069 (1993-09-01), McManus
patent: 5872250 (1999-02-01), Williams et al.
patent: 2 070 555 (1996-12-01), None
patent: 2 091 381 (1997-09-01), None
patent: 2 130 938 (1999-05-01), None
Nicholas D. Cheronis, 1958, “Semicro Experimental Organic Chemistry”, Chapter 5.
M. Connolly et al,J. Pharm Sci.; 84, 174-177 (1996).

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