Process for the preparation of citalopram

Details Process for the preparation of citalopram Process for the preparation of citalopram

2006-02-21

2006-02-21

Owens, Amelia A. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S469000

Reexamination Certificate

active

07002025

ABSTRACT:
Preparation of citalopram comprises the steps of: (a) converting the compound of Formula (I) to a compound of Formula (II), wherein R in Formula (I) represents a C2to C5alkylene group which may be substituted or unsubstituted, and R1in the compounds of Formula (II) represents a carboxylic acid group or a salt or an ester thereof; and (b) converting the compound of Formula (II) to form citalopram or a pharmaceutically acceptable salt thereof, or a direct conversion of the compound of Formula (I) to citalopram

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