Process for the preparation of cinnamic acid esters

Details Process for the preparation of cinnamic acid esters Process for the preparation of cinnamic acid esters

1998-10-14

2000-04-25

Geist, Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 6700

Patent

active

060546077

ABSTRACT:
A process for the preparation of a cinnamic acid ester comprises condensing a benzaldehyde with an acetic acid ester in the presence of a base. The reaction mixture is then treated, without adding an additional solvent or after adding an additional solvent, with an acid to convert a 3-alkoxy-3-phenylpropionic acid ester in the reaction mixture into a corresponding cinnamic acid ester. This procedure allows cinnamic acid ester derivatives of high-purity to be obtained in good yield.

REFERENCES:
patent: 4618698 (1986-10-01), Beitzke
patent: 5359122 (1994-10-01), Huellmann et al.
patent: 5527947 (1996-06-01), Alexander et al.
Marvel et al, "Ethly Cinnamate", Organic Syntheses, Collective vol. I, pp. 252-254 (1932).
Marvel et al "Ethyl Cinnamate", Organic Synthesis Coll., vol. 1, pp. 252-254.
A.d. Wissensch, "L. Claisen: Zur Darstellung der Zimmtsaure und ihrer Homologen", Ber., 23, pp. 976-978 (1890).
Gurjar et al. (Indian J. Chemistry; Section B; 14B(7); pp. 548-549), 1976.

Affiliated with

Also associated with

Rating

Process for the preparation of cinnamic acid esters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of cinnamic acid esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of cinnamic acid esters will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-994510