Process for the preparation of cholesterol derivatives

Details Process for the preparation of cholesterol derivatives Process for the preparation of cholesterol derivatives

1980-06-03

1981-12-08

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

043047262

ABSTRACT:
New organic dibasic acid half esters of 7-ketocholesterol and of 7-hydroxycholesterol represented by the general formula ##STR1## (wherein R.sub.1 is .dbd.O or --OH and R.sub.2 is a C.sub.1 -C.sub.5 alkylene group or a phenylene group) and physiologically acceptable salts thereof. These compounds are effective as an immunosuppressive or an anti-inflammatory agent.

REFERENCES:
patent: 4157391 (1979-06-01), Kitame et al.
patent: 4189400 (1980-02-01), Proksch et al.
patent: 4202891 (1980-05-01), Schroepfer et al.
patent: 4225525 (1980-09-01), Baggiolini et al.
"Steroid Reactors" by Djerossi et al. (1963) pp. 114, 115.

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