Process for the preparation of choleragen

Details Process for the preparation of choleragen Process for the preparation of choleragen

1974-12-19

1976-08-03

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 92, A61K 3902, C07G 700

Patent

active

039728587

ABSTRACT:
The invention relates to a process for preparing choleragen, which comprises adding silicic acid to a solution containing choleragen, stirring the suspension, separating the silicic acid, treating for elution with an aqueous salt or buffer solution, and separating the choleragen-containing eluate from the silicic acid.

REFERENCES:
patent: 3686395 (1972-08-01), Stephan
J. Exptl. Med.; 1969, Finkelstein et al., pp. 185-202.
Science, vol. 175, 1972, Finkelstein et al.

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