Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1985-03-15
1987-09-22
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435254, 435913, C12N 114, C12P 1718, C12R 166
Patent
active
046955445
ABSTRACT:
A process for preparing the compound having Formula I and several minor related compounds. ##STR1## The compound of Formula I and the several minor related compounds are antagonists of cholecystokinin (CCK). CCK antagonists are useful in the treatment and prevention of disorders of the gastrointestinal, central nervous and appetite regulatory systems of animals, especially humans.
REFERENCES:
patent: 3944470 (1976-03-01), Diehl et al.
Chien et al.; "Microbial Transformations of Natural Antitumor Agents: Use of Solubilizing Agents to Improve Yields of Hydroxylated Ellipticines"; Applied and Environmental Microbiology, vol. 40, No. 4, Oct. 1980, pp. 741-745.
Chang Raymond S.
Goetz Michael A.
Monaghan Richard L.
Abrams Samuel B.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Weimar Elizabeth C.
Wiseman Thomas G.
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