Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2004-03-15
2008-12-23
Puttlitz, Karl J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S337000, C548S262400
Reexamination Certificate
active
07468459
ABSTRACT:
The present invention relates to a process for the efficient preparation of enantiomerically enriched beta amino acid derivatives which are useful in the asymmetric synthesis of biologically active molecules. The process comprises an enantioselective hydrogenation of a prochiral beta amino acrylic acid derivative substrate in the presence of a transition metal precursor complexed with a chiral ferrocenyl diphosphine ligand.
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Armstrong, III Joseph D.
Krska Shane W.
Njolito Eugenia
Rivera Nelo R.
Rosner Thorsten
Durette Philippe L.
Fitch Catherine D.
Merck & Co. , Inc.
Puttlitz Karl J
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