Process for the preparation of chiral...

Details Process for the preparation of chiral... Process for the preparation of chiral...

2005-11-04

2010-10-26

Berch, Mark L (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

C544S270000, C544S272000, C546S200000

Reexamination Certificate

active

07820815

ABSTRACT:
The invention relates to an improved process for preparing enantiomerically pure 8-(3-aminopiperidin-1-yl)-xanthines. The process involves reacting a compound of the formula (III) with 3-(phthalimido)piperidine or an enantiomer thereofwhere X is a leaving group selected from halogens and sulphonic ester acid residues, and R1to R3are as defined herein, to obtain a compound of the formula (II)and deprotecting the obtained compound of the formula (II) to obtain the product xanthines.

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