Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1991-10-25
1993-04-20
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435911, C12P 1712, C12N 114, C07D21146
Patent
active
052042499
ABSTRACT:
The invention relates to a novel process for the preparation of carebastine and similar materials from ebastine or terfenadine by oxidization using microorganisms. Carebastine and similar materials are used for the treatment of allergic disorders and as antihistamines.
REFERENCES:
patent: 3822188 (1974-07-01), Fager et al.
patent: 4064009 (1977-12-01), Fukuda et al.
patent: 4153509 (1979-05-01), Schwartz
patent: 4996149 (1991-02-01), Jarreau et al.
ATCC "Catalogue of Fungi/Yeasts" 17th Ed. 1987 pp. 126-127.
Bottcher Henning
Schwartz Harry
Lilling Herbert J.
Merck Patent Gesellschaft mit beschrankter Haftung
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