Process for the preparation of biologically active material cont

Details Process for the preparation of biologically active material cont Process for the preparation of biologically active material cont

1993-02-16

1995-02-14

Kishore, G. S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424489, 264 41, 264 46, A61K 948, A61K 914, B01J 1304, B01J 1320

Patent

active

053893794

ABSTRACT:
A process for the preparation of microcapsules containing biologically active material is disclosed. The process involves dissolving a polymer into a solvent into which the active material is also introduced; atomizing the resulting suspension or solution and collecting the droplets in a non-solvent for the polymeric droplets containing active material, resulting in coagulation. Subsequently, the coagulated droplets are hardened in a second non-solvent.

REFERENCES:
patent: 4389330 (1983-06-01), Tice et al.
patent: 4897267 (1990-01-01), Bontemps et al.
patent: 5091187 (1993-02-01), Haynes
Sefton et al., Journal of Pharaceutical Sciences, "Ethylene-Vinyl Acetate Copolymer Microspheres for Controlled Release of Macromolecules", vol. 73, No. 12, Dec., 1984.
C.E., vol. 97 (Nov., 1990).

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