Process for the preparation of basically substituted phenylaceto

Details Process for the preparation of basically substituted phenylaceto Process for the preparation of basically substituted phenylaceto

1985-06-03

1987-09-29

Torrence, Dolph H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

558342, 558390, C07C12178

Patent

active

046970355

ABSTRACT:
A simplified process for the preparation of basically substituted phenylacetonitriles, in particular of verapamil, is described. This process is carried out with fewer stages and higher yields than the known processes according to the state of the art.

REFERENCES:
patent: 3261859 (1966-07-01), Dengel
patent: 4350636 (1982-09-01), Kastner
The Chemistry of the Cyano Group, by Zvi Rappoport, 1970, p. 380.

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