Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-12-24
1992-02-04
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
540310, 546113, 546115, 548453, 548455, C07D48704
Patent
active
050861700
ABSTRACT:
A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, alkyl and hydroxyalkyl of 1 to 5 carbon atoms and amino, n is an integer from 1 to 3, X and X.sub.1 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms or taken together with the carbon atom to which they are attached are ##STR2## Y is --O-- or --S--, R.sub.3 is alkyl of 1 to 3 carbon atoms or aryl of 6 to 8 carbon atoms, ##STR3## is selected from the group consisting of ##STR4## R.sub.4 and R.sub.5 are individually aryl unsubstituted or substituted with at least one member of the group consisting of halogen, --NO.sub.2 and alkyl and alkoxy of 1 to 3 carbon atoms and non-toxic, pharmaceutically acceptable salts thereof with acids and bases having cyclooxygenase inhibiting and antibiotic acitvity.
REFERENCES:
patent: 4272439 (1981-06-01), Gingaly et al.
patent: 4576939 (1986-03-01), Ross et al.
Kennewell Peter D.
Luheshi Abdul B. N.
Smalley Robert K.
Westwood Robert
Rizzo Nicholas S.
Roussel Uclaf
LandOfFree
Process for the preparation of azabicyclo compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the preparation of azabicyclo compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of azabicyclo compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-348844