Process for the preparation of arylethylamines and substituted a

Details Process for the preparation of arylethylamines and substituted a Process for the preparation of arylethylamines and substituted a

1992-03-30

1993-06-15

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

562 59, 562 66, 562125, 564323, 564337, 564374, 564378, 564382, C07C20940

Patent

active

052200671

ABSTRACT:
This invention provides a process for directly preparing hydrohalide salts of arylethylamines from (.alpha.-chloro-.alpha.-oximino)acetophenones. The process involves hydrogenation in presence of a transition metal catalyst in an organic acid in substantial absence of moisture. The process is illustrated by conversion of 4-hydroxy (.alpha.-chloro-.alpha.-oximino)acetophenone to Tyramine hydrochloride: ##STR1##

REFERENCES:
patent: 5041669 (1991-08-01), Tafesh et al.

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