Process for the preparation of arylalkynyl-N-hydroxyurea derivat

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564 52, C07C27504, C07C27518

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active

057146330

ABSTRACT:
The present invention provides a process for the preparation of a compound of formula ##STR1## wherein R is a straight or branched alkyl group of from one to twelve carbon atoms; M represents hydrogen or a pharmaceutically acceptable cation; and A is selected from optionally substituted carbocyclic phenyl.

REFERENCES:
patent: 5185363 (1993-02-01), Brooks et al.
patent: 5288751 (1994-02-01), Brooks et al.
patent: 5476873 (1995-12-01), Brooks et al.
patent: 5559144 (1996-09-01), Brooks et al.
PCT International Search Report corresponding to PCT/US96/13892, 1996.
Lee et al.; J. Org. Chem 1993 48, 24-31.

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