Process for the preparation of anti-inflammatory pharmaceutical

Details Process for the preparation of anti-inflammatory pharmaceutical Process for the preparation of anti-inflammatory pharmaceutical

1989-06-13

1993-01-19

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

514570, A61K 946, A61K 3119

Patent

active

051805901

ABSTRACT:
Anti-inflammatory pharmaceutical compositions with an ibuprofen base which eliminate the bitter taste, the burning in the throat and the topical toxicity at the level of the intestinal wall when their effervescent aqueous solutions are taken. The proportions among the main ingredients of each dose are the following: ibuprofen, 200 to 800 mg or ibuprofen sodium salt, 221.3 to 885.2 mg; sodium bicarbonate, 2.100 to 8.402 g; and citric acid, 0.450 to 1.800 g.

REFERENCES:
patent: 4806358 (1989-02-01), Khan
patent: 5055306 (1991-10-01), Barry
Barry et al., "Sustained-release granular . . . " CA 112(6) 62596k (1990).

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