Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1984-08-10
1986-09-23
Raymond, Richard L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2603515, C07C 49423, C07C 5022, C07C 5024
Patent
active
046134646
ABSTRACT:
The present invention relates to a new process for the preparation of anthracyclinones of the formula ##STR1## in which R denotes C.sub.1 -C.sub.4 -alkyl, R.sub.1 denotes H or OH, and R.sub.2 and R.sub.3 are different and each represent H or OH, and R.sub.4 and R.sub.5 are different and each represent H or OH, starting from a compound of the formula ##STR2## in which R.sub.1 and R have the abovementioned meaning. The compounds of the formula I are valuable intermediates in the preparation of the corresponding glycosides having cytostatic efficacy.
REFERENCES:
patent: 4215062 (1980-07-01), Mitscher
patent: 4312811 (1982-01-01), Schoemans et al.
patent: 4536336 (1985-08-01), Kishi
Behnke Bert
Krohn Karsten
Covington Raymond
Hoechst Aktiengesellschaft
Raymond Richard L.
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