Process for the preparation of an organ-specific substance label

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound

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Details

424 149, 424 111, 206569, A61K 5100, A61M 3614

Patent

active

057231028

ABSTRACT:
The invention relates to a process for the preparation of an organ-specific substance labeled with technetium-99m, in which an organ-specific substance, or an organ-specific substance which has been pretreated or coupled to a complexing agent for technetium-99m, is mixed with

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patent: 5053493 (1991-10-01), Pak et al.
patent: 5061641 (1991-10-01), Shochat et al.
patent: 5102990 (1992-04-01), Rhodes
A. Bardy et al., Technetium-99m Labeling by Means of Stannous Pyrophosphate, J. Nucl. Med., 16(5):435-437 (1975).
A. Khentigan et al., Effects of Prior Administration of Sn(11) Complexes on In Vivo Distribution of 99m-Tc-Pertechnetate, J. Nucl. Med., 17(5): 380-384 (1975).
B.A. Rhodes et al., 99mTc-Labeling and Acceptance Testing of Radiolabeled Antibodies and Antibody Fragments, Tumor Imaging 111-123 (1982).
William A. Pettit et al., Radiolabeling of Affinity-Purified Goat Anti-Carcinoembryonic Antigen Immunoglobulin G with Technetium-99m, Cancer Research, 40:3043-3045 (1980).

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