Process for the preparation of an optically pure tetrahydroquino

Details Process for the preparation of an optically pure tetrahydroquino Process for the preparation of an optically pure tetrahydroquino

1997-07-23

1999-05-18

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D217/16

Patent

active

059051558

ABSTRACT:
A process for the preparation of optically pure (-)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid by reaction of L-phenylalanine with formaldehyde in aqueous solution or paraformaldehyde in the presence of hydroiodic acid is described.

REFERENCES:
patent: 5602255 (1997-02-01), Kuge
patent: 5610307 (1997-03-01), Erickson
patent: 5627282 (1997-05-01), Kwon et al.
Fiesers' Reagents for Organic Synthesis, vol. 9, p. 238, 1981.

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