Process for the preparation of an optically active...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S350000, C544S360000, C546S268100

Reexamination Certificate

active

07863273

ABSTRACT:
A substantially pure dextrorotatory isomer of zopiclone or a pharmaceutically acceptable salt thereof and crystalline forms thereof are provided. Also provided is a process for its preparation and pharmaceutical compositions containing same.

REFERENCES:
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patent: 6436936 (2002-08-01), Young et al.
patent: 6444673 (2002-09-01), Cotrel et al.
patent: 6969767 (2005-11-01), Bayod et al.
patent: 1 457 487 (2004-09-01), None
patent: WO 93/16035 (1993-08-01), None
patent: WO 2005/047274 (2005-05-01), None
patent: WO 2005/097132 (2005-10-01), None
Yaping et al., “Synthesis of enantiomerically pure desmethylzopiclone and determination of its absolute configuration”,Tetrahedron: Asymmetry, vol. 11, 2000, pp. 4623-4627.
Wilen et al., “Tetrahedron report No. 38: Strategies in optical resolutions”,Tetrahedron, Elsevier Science Publishers, vol. 33, No. 21, 1977, pp. 2725-2736.

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