Process for the preparation of amino acids by using...

Details Process for the preparation of amino acids by using... Process for the preparation of amino acids by using...

2005-07-26

2005-07-26

Kerr, Kathleen (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S115000

Reexamination Certificate

active

06921651

ABSTRACT:
The invention relates to a process for the preparation of L-amino acids. The process includes fermenting the coryneform bacteria producing the desired L-amino acid, in which at least the gene coding for 6-phosphofructokinase and/or the gene coding for 1-phosphofructokinase are/is attenuated, enriching the desired L-amino acid in the medium or in the cells of the bacteria, and isolating the L-amino acid. Optionally bacteria are employed in which, in addition, further genes of the biosynthetic pathway of the desired L-amino acid are enhanced, or bacteria are employed in which the metabolic pathways that diminish the formation of the desired L-amino acid are at least partly switched off.

REFERENCES:
patent: 6465238 (2002-10-01), Hanke
patent: 10135051 (2003-02-01), None
patent: 1 103 613 (2001-05-01), None
patent: 1 106 622 (2001-06-01), None
patent: 1 108 790 (2001-06-01), None
patent: 63 102692 (1988-05-01), None
patent: WO 00/77172 (2000-12-01), None

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