Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Process involving micro-organisms of different genera in the...
Patent
1985-07-01
1988-02-16
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Process involving micro-organisms of different genera in the...
435191, 435853, 435921, 426 52, 426 53, 426 12, C12P 3900, C12N 906, C12R 1225, C12R 172, C12G 100, A23K 100
Patent
active
047255404
ABSTRACT:
A process for the preparation of histaminase, respectively a histaminase containing material, is described. Histaminase is a diamine-oxidase which metabolizes histamine.
According to the process at least one microorganism which produces in its cells histaminase, is cultivated and as soon as a sufficient number of microorganisms has grown, the microorganisms are isolated from the culture medium. Adhering culture medium is removed from the microorganisms and the microorganism cells are broken up and comminuted.
The product can be dried in the vacuum, cooled and stored or it can be used to produce products having a higher content of histaminase or to produce a pure histaminase.
Preferably a mixture of microorganisms is cultivated which contains at least one microorganism selected from the group lactobacillus and at least one yeast selected from the group candida.
The histaminase containing products, respectively the histaminase, are used for metabolizing histamine in foodstuffs, beverages and forages yielding corresponding histamine free products in which the histamine had been metabolized forming not harmful metabolization products.
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Chemical Abstracts, 99, 19342d, J. Green, "Serological differences . . . ", 1983.
Chemical Abstracts, 96, 100569t (1982), G. W. Haywood, "Microbial oxidation of amines . . . ".
Lembke Andreas
Underberg Emil
Emil Underberg
Shapiro Lionel M.
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