Process for the preparation of .alpha.-methyl-2-thiopheneacetic

Details Process for the preparation of .alpha.-methyl-2-thiopheneacetic Process for the preparation of .alpha.-methyl-2-thiopheneacetic

1996-06-14

1997-07-22

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 73, C07D33322

Patent

active

056505221

ABSTRACT:
Process for the preparation of derivatives having general formula (I) ##STR1## wherein the meaning of R will be defined in the text, characterized by the reaction between a compound having formula ##STR2## wherein X is an halogen, and an alkaline salt of a methyl dialkylmalonate.

REFERENCES:
patent: 4159986 (1979-07-01), Clemence et al.
patent: 4690945 (1987-09-01), Arechaga et al.
patent: 5073184 (1991-12-01), Anthony et al.
European Journal of Medicinal Chemistrychimica Therapeutical. vol. 9, No. 4, 1974, Paris, France, pp. 390-396.
"Advanced Organic Chemistry; Reactions, Mechanisms, and Structure" Third Edition, 1985, John Wiley & Sons, Inc, New York, US.

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