Process for the preparation of alkylphosphocholines and the prod

Details Process for the preparation of alkylphosphocholines and the prod Process for the preparation of alkylphosphocholines and the prod

1999-04-22

2000-02-22

Ambrose, Michael G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

558 99, 558166, 558146, C07F 910

Patent

active

060282096

ABSTRACT:
A process for the preparation of C.sub.14 -C.sub.18 -alkylphosphocholines by reacting an n-alkanol with a chain length of C.sub.14 -C.sub.18 with phosphorus oxychloride in an inert solvent or also without solvent in the presence or absence of a basic substance in a single vessel process and subsequent reaction of the reaction product in an inert solvent with a choline salt in the presence of a basic substance to form phosphoric acid diester chloride, subsequent hydrolysis and isolation of alkylphosphocholine as well as optionally purification using a mixed-bed ion exchanger or in successive steps with an acid ion exchanger and a basic ion exchanger.

REFERENCES:
patent: 4130571 (1978-12-01), Nakajima et al.
patent: 4492659 (1985-01-01), Bosies et al.
patent: 5916884 (1999-06-01), Eibl

Affiliated with

Also associated with

Rating

Process for the preparation of alkylphosphocholines and the prod does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of alkylphosphocholines and the prod, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of alkylphosphocholines and the prod will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-521853