Process for the preparation of alkaloids of the leurosine type

Details Process for the preparation of alkaloids of the leurosine type Process for the preparation of alkaloids of the leurosine type

1978-05-19

1980-04-22

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D51904

Patent

active

041995058

ABSTRACT:
A process for the preparation of alkaloids of the leurosine type having the formula I ##STR1## and the acid addition salts thereof. In the formula I R is hydrogen or methyl. The compounds prepared according to the invention are known compounds showing cytostatic activity.

REFERENCES:
patent: 3716541 (1973-02-01), Dobson et al.
March, "Advanced Organic Chemistry" (1968), pp. 618-621 and 720-721. _
Morrison et al., "Organic Chemistry" (1966), pp. 885-887.

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