Process for the preparation of aldehydes from organic halides

Details Process for the preparation of aldehydes from organic halides Process for the preparation of aldehydes from organic halides

1974-10-10

1976-06-01

Patten, James A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260289R, 260290P, 26032616, 2603323R, 260465R, 260476R, 260562R, 260599, 260600R, C07C 4500

Patent

active

039609324

ABSTRACT:
Aldehydes are obtained from aryl, vinylic and heterocyclic halides and substituted derivatives thereof, a tertiary amine, carbon monoxide and hydrogen at from about 50.degree.-175.degree.C under from about one to 200 atmospheres pressure and with PdX.sub.2 [P(C.sub.6 H.sub.5).sub.3 ].sub.1 or 2 as a catalyst where X is acetate or a halogen. The ratios of carbon monoxide to hydrogen are not critical but the most favorable reactions are usually obtained with ratio from about 0.1 to about 10. A typical example is the conversion of p-bromoanisole to anisaldehyde in 84% yield at 150.degree.C in 18 hrs. at 1000 psig. of 1:1 CO to H.sub.2 with one mole percent of PdBr.sub.2 [P(C.sub.6 H.sub.5).sub.3 ].sub.2 as catalyst and with tri-n-butylamine as the tertiary amine.

REFERENCES:
falbe, Carbon Monoxide in Org. Syn., (1970), pp. 118-120.
Maitlis, The Organic Chemistry of Palladium, Vol. II, (1971), p. 24.

Affiliated with

Also associated with

Rating

Process for the preparation of aldehydes from organic halides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of aldehydes from organic halides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of aldehydes from organic halides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2402848