Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-07-11
1976-03-23
Randolph, John D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602472A, 2602472R, 26029369, 2602949, 2602955R, 2602391, 260243C, 424246, 424248, 424250, 424263, 424267, C07D41914, C07D41304, C07D41314, C07D40104
Patent
active
039460150
ABSTRACT:
A process for the production of 6-(disubstituted amino)phenyl-1,2-dihydro-2-oxonicotinyl chloride hydrochlorides, which comprises exposing the dry, finely divided corresponding 6-(disubstituted amino)phenyl-1,2-dihydro-2-oxonicotinic acid or its hydrochloride to gaseous thionyl chloride utilizing reduced atmospheric pressures. The 6-(disubstituted amino)phenyl-1,2-dihydro-2-oxonicotinyl chloride hydrochlorides are useful as intermediates in the preparation of useful semisynthetic antibiotics.
REFERENCES:
patent: 3503986 (1970-03-01), Seidel et al.
patent: 3576814 (1971-04-01), Seidel et al.
Bond Robert T.
Parke, Davis & Company
Randolph John D.
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