Process for the preparation of a substituted 2.5-diamino-3-hydro

Details Process for the preparation of a substituted 2.5-diamino-3-hydro Process for the preparation of a substituted 2.5-diamino-3-hydro

1996-03-28

1998-07-28

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 26100

Patent

active

057865000

ABSTRACT:
Intermediates and processes are disclosed which are useful for the preparation of a substantially pure compound of the formula: ##STR1## wherein R.sub.6 and R.sub.7 are each hydrogen or R.sub.6 and R.sub.7 are independently selected from ##STR2## wherein R.sub.a and R.sub.b are independently selected from hydrogen, loweralkyl and phenyl and R.sub.c, R.sub.d and R.sub.e are independently selected from hydrogen, loweralkyl, trifluoromethyl, alkoxy, halo and phenyl; and ##STR3## wherein the naphthyl ring is unsubstituted or substituted with one, two or three substituents independently selected from loweralkyl, trifluoromethyl, alkoxy and halo; or

REFERENCES:
patent: 2784228 (1957-03-01), Hartung
patent: 5142056 (1992-08-01), Kempf et al.
patent: 5354866 (1994-10-01), Kempf et al.
patent: 5559158 (1996-09-01), Al-Razzak et al.
Ghosh, et al., J. Org. Chem. 58 1025 1993.
Brillon, et al., J. Org. Chem. 57 1838 (1992).
Stuk, et al., J. Org. Chem. 59 4040-4041 (1994).

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