Process for the preparation of a renin inhibiting compound

Details Process for the preparation of a renin inhibiting compound Process for the preparation of a renin inhibiting compound

1993-10-05

1994-09-06

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

514252, 544369, 564355, 564356, 564357, 564413, 564445, 564446, 564450, 564453, 564507, 549451, C07C20900, C07C31700

Patent

active

053449908

ABSTRACT:
Intermediates and a process for their preparation are disclosed which are useful for the preparation of a renin inhibiting compound of the formula: ##STR1## wherein R is a nitrogen-containing heterocycle which is bonded via a nitrogen atom to the sulfonyl group, R.sub.6 is hydrogen, alkoxy, halogen or loweralkyl, R.sub.7 is loweralkyl having 2 to 7 carbon atoms, and R.sub.8 is loweralkyl, cycloalkyl, or aryl or a pharmaceutically acceptable acid addition salt thereof.

REFERENCES:
patent: 4845079 (1989-07-01), Luly et al.
Bose et al., CA 102:220618x (1985).
Deshong et al., CA 102:167035b (1984).
Deshong et al., CA 101:131016m (1984).
Fronza et al., CA 100:175169x (1983).
Fuganti et al., CA 98:143762j (1983).
Deshong et al., CA 98:126525s (1983).
Fronza et al., CA 96:200056s (1981).
Baker et al., CA 119:9157q (1993).
Baker et al., CA 116:236150p (1992).
Brandi et al., CA 116:59498k (1991).
Kita et al., CA 112:99059s (1989).
Taguchi et al., CA 110:193270j (1988).
Fronza et al., CA 109:190714a (1988).
Tamura et al., CA 109:149792m (1988).
Kita et al., CA 107(25):237181a (1987).
Luly, et al., J. Org. Chem., 53, 6109 (1988).
Luly, et al., J. Med. Chem., 31, 2264 (1988).
Wood, et al., Tetrahedron Letters, 31, 6329 (1990).
Taguchi, et al., Tetrahedron Letters, 29, 5291 (1988).

Affiliated with

Also associated with

Rating

Process for the preparation of a renin inhibiting compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of a renin inhibiting compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of a renin inhibiting compound will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1330607