Process for the preparation of a renin inhibiting compound

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...

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435106, 435116, 435117, 435122, 435128, 435130, 544 59, 544159, 544383, 546216, 548541, 548952, 548204, 562479, C12P 1304, C12P 1712, C12P 1100, C07D24104

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052759504

ABSTRACT:
Intermediates and a process for their preparation are disclosed which are useful for the preparation of a renin inhibiting compound of the formula: ##STR1## wherein R is a nitrogen-containing heterocycle which is bonded via a nitrogen atom to the sulfonyl group, R.sub.6 is hydrogen, alkoxy, halogen or loweralkyl, R.sub.7 is loweralkyl having 2 to 7 carbon atoms, and R.sub.8 is loweralkyl, cycloalkyl, or aryl or a pharmaceutically acceptable acid addition salt thereof.

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