Process for the preparation of a rabies vaccine and vaccine obta

Details Process for the preparation of a rabies vaccine and vaccine obta Process for the preparation of a rabies vaccine and vaccine obta

1980-04-02

1981-03-10

Rose, Shep K.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

Recovery or purification

424 89, A61K 39205

Patent

active

042555205

ABSTRACT:
A method for preparing a rabies vaccine wherein rabies viruses are multiplied in poultry embryos, the heads of the embryos are harvested and the cell extract containing the rabies antigens is separated therefrom for differential centrifugation and density gradient centrifugation, the separated antigen is further processed using conventional methods. This process results in a highly selective concentration of antigens and the production of viruses having a very high activity and freedom from contaminating proteins.

REFERENCES:
patent: 2204064 (1940-06-01), Beard
patent: 2445300 (1948-06-01), Chambers
patent: 2506345 (1950-05-01), Cox et al.
patent: 2768114 (1956-10-01), Koprowski et al.
patent: 2773800 (1956-12-01), Powell
patent: 3029190 (1962-04-01), Hanson et al.
patent: 3143470 (1964-08-01), Wilner
patent: 3155589 (1964-11-01), Slater
patent: 3156620 (1964-11-01), Sharpless
patent: 3255080 (1966-06-01), Emery
patent: 3397267 (1968-08-01), Fernandes et al.
patent: 3415926 (1968-12-01), Hays et al.
patent: 3585266 (1971-06-01), Emery et al.
patent: 3674862 (1972-07-01), Lavender
patent: 3859168 (1975-01-01), Barth et al.
patent: 3973000 (1976-08-01), Cavender
patent: 4040904 (1977-08-01), Slater
patent: 4071618 (1978-01-01), Konobe et al.
patent: 4115195 (1978-09-01), Barth et al.
Bernkopf, H. et al., PSEBM 45: 332 (1940), Characteristics of Fixed Rabies Virus Cultivated on Developing Chick Embryos.
Schell, K. R., A Highly Purified and Concentrated Duck Embryo Vaccine 80th Ann. mtg., Miami Beach, Fla., U.S.A., May 11-16, 1980, Abstr. Annu. Meet AM-Soc. Microbiol. 80(0), 1980, Abstract 821.
Lavender et al., Appl. Microbiol. 22 (3), 1971, 358-365, Zonal Contrifuged Purified Duck Embryo Cell Culture Rabies Vaccine for Human Vaccination.
Kamada Jap, JVETRES, 19 (1-2), 1971, 37-38, Characterization of Multiplication of Avian Encephalomyelitis Virus in Chick Embryo Brain Cell Cultures.
Kuchler Biochemical Methods in Cell Culture and Virology, 1977, Dowden Hutchinson Rossine, pp. 10, 123-130.
Cox Growth of Viruses and Rickettsiae in the Developing Chick Embryo Ann. N.Y. Acad. Sci., vol. 55, Art 2, 236-247 (1952).
Beveridge et al., The Cultivation of Virus and Rickettsiae in the Chick Embryo Med. Res. Counc. G.B. Spec. Rep. Serv. 256 (1946), 92, pp. USPTO#QR66B4 esp., pp. V-VII, 1-39, 67 (Rabies).
Sigurdsson, B. J., Exp. Med. 78:341 (1943) Yield of Rabies Virus in Chick Embryo.
Kliglerij, et al. Nature 143: 899 (1939), Cultivation of Rabies Virus in Developing Chick Embryo.
Dawson, Jr., Amer. J. Path. 17: 177 (1941), Study of Chick Embryo-Adapted Rabies Virus.
Dawson, Jr. Science 89: 300 (1939), Infection of Chicks and Chick Embryos with Rabies.

Affiliated with

Also associated with

Rating

Process for the preparation of a rabies vaccine and vaccine obta does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of a rabies vaccine and vaccine obta, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of a rabies vaccine and vaccine obta will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1294863