Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-04-10
1997-12-02
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D48722
Patent
active
056937890
ABSTRACT:
The present invention provides a process for the preparation of BPD 1,4-diene diester A-ring comprising reacting hematoporphyrin IX dimethyl ester with dimethyl acetylenedicarboxylate followed by purification of the product by a series of fractional crystallizations.
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Pangka, V.S., et al., "Diels-Alder Reactions of Protoporphyrin IX Dimethyl Ester with Electron-Deficient Alkynes", J. Org. Chem., 51:1094-1100 (1986) .
Johnston Annette A.
Lindbeck Aline C.
Monte William T.
Wang Xiu C.
Abbott Laboratories
Shah Mukund J.
Sripada Pavanaram K.
Ward Michael J.
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