Process for the preparation of a macrolide compound

Details Process for the preparation of a macrolide compound Process for the preparation of a macrolide compound

1988-09-09

1990-05-01

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31300

Patent

active

049219782

ABSTRACT:
A process for preparing the compound of formula (I) ##STR1## which comprises treating the corresponding 23.alpha.-compound sequentially with (i) oxalyl chloride and (ii) 2-mercaptopyridine-N-oxide, a catalytic amount of an organic base, and a thiol.

REFERENCES:
patent: 4579864 (1986-04-01), Linn et al.
patent: 4581345 (1986-04-01), Wyvratt, Jr.

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