Process for the preparation of a biologically active extract

Details Process for the preparation of a biologically active extract Process for the preparation of a biologically active extract

1984-09-19

1986-03-18

Niebling, John F.

Chemistry: electrical and wave energy

Processes and products

Electrostatic field or electrical discharge

2041824, 424 95, 424101, 424103, 424105, 424106, 424107, B01D 1302

Patent

active

045766967

ABSTRACT:
A mammal organ, for example the thymus, or a cell culture is comminuted to form a slurry, accompanied by cell disintegration, high molecular weight substances are precipitated by heating and removed by centrifuging, and residual substances of molecular weight greater than 10,000 are separated out by ultrafiltration; finally, the salts are substantially removed by electrodialysis. A biologically active, low-salt, sterile, pyrogen-free and antigen-free complete extract is obtained and, in contrast to all known processes, no foreign substance or auxiliary, other than water--not even a preservative or a carrier for separation methods--is used.

REFERENCES:
patent: 3799806 (1974-03-01), Madsen
patent: 4054648 (1977-10-01), Nagasawa et al.

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