Process for the preparation of a 2-alkylpyrimidine

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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C07D23926

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046670343

ABSTRACT:
The process according to the invention for the preparation of a 2-propyl- or 2-butylpyrimidine, in which the corresponding 2-alkyl-1,4,5,6-tetrahydropyrimidine is dehydrogenated in the gas phase with a palladium-containing catalyst and in which a 2-propyl- or 2-butylpyrimidine is recovered from the reaction mixture, is characterized in that the gas-phase reaction is carried out using a carbon monoxide-hydrogen reactant. As this is understood a mixture of carbon monoxide and hydrogen and/or a compound capable of at least partial decomposing into CO and H.sub.2 under the reaction conditions.

REFERENCES:
patent: 4127652 (1978-11-01), Maurer et al.
patent: 4376201 (1983-03-01), Pews
patent: 4493929 (1985-01-01), Pews

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