Process for the preparation of 9-amino substituted...

Details Process for the preparation of 9-amino substituted... Process for the preparation of 9-amino substituted...

2006-07-18

2006-07-18

Coleman, Brenda (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07078521

ABSTRACT:
A process is described for the preparation of compounds with the following formula where the groups are as defined below; in particular, R1is a substituted amine; said process includes essentially the reaction of pyrrolobenzothiazepin-9-one with amine R1H to give the corresponding enamine, which is subsequently transformed into the final compound

REFERENCES:
patent: 6391870 (2002-05-01), Campiani et al.
patent: WO 00/06579 (2000-02-01), None
Campiani et al., New Antipsychotic Agents with Serotonin Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure, Journal of Medicinal Chemistry, vol. 41, No. 20, pp. 3763-3772, Sep. 24, 1998.

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