Process for the preparation of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S028500, C536S028510, C536S028520, C536S028530, C536S028540, C536S028100, C536S025300, C536S028300

Reexamination Certificate

active

06894159

ABSTRACT:
The present invention relates to a novel and improved process for preparing 2′-fluoro-5-methyl-β-L-arabinofuranosyluridine represented by formula (1) which shows anti-viral activity, especially potent anti-viral activity against hepatitis B-virus and Epstein-Barr virus:

REFERENCES:
patent: 5565438 (1996-10-01), Chu et al.
patent: 5567688 (1996-10-01), Chu et al.
patent: 5587362 (1996-12-01), Chu et al.
patent: 5808040 (1998-09-01), Chu et al.
patent: 6512107 (2003-01-01), Chu et al.
patent: 149472 (1973-07-01), None
patent: 275890 (1992-03-01), None
patent: 1327637 (2003-07-01), None
patent: WO 8907602 (1989-08-01), None
patent: WO 9520595 (1995-08-01), None
patent: WO 9905157 (1999-02-01), None
patent: WO 9905158 (1999-02-01), None
Abe, Y., et al., “Epimerization of Aldoss Catalyzed By Dioxobis (2,4-Pentanedionato-O,O')Molybdenum(VI). An Improved Procedure for C-2 Epimer Preparation,”Chem. Pharm. Bull., 28(4):1324-1326 (1980). Provided asChem. Abs. AN 1980:495507 (DN 93:95507).
Bilik, V., et al., “Reactions of Saccharides Catalyzed by Molybdate Ions. VII. Preparation of L-Ribose, D-and L-Lyxose,”Chem. Zvesti, 27(4):547-550 (1973). Provided asChem. Abs. AN 1974:83428 (DN 80:83428).
Greene et al.,Protective Groups in Organic Synthesis, 2nd ed., John Wiley, 1991.
Jung, M., et al., “Efficient Synthesis of L-Ribose and 2-Deoxy L-Ribose from D-Ribose and L-Arabinose,”Tetrahedron Lett., (Elsevier Science Publishers), 38(24):4199-4202 (1997).
Lin, T.-S., et al., “Synthesis of Several Pyrimidine L-Nucleoside Analogues as Potential Antiviral Agents,”Tetrahedron, 51(4):1055-1068 (Jan. 23, 1995).
Visser, G.M., et al., “Synthesis of the Mirror Image of the RNA Fragment D-CAAGG: a Model Compound to Study Interactions Between Oligonucleotides of Opposite Handedness,”Recl. Trav. Chim. Pays-Bas, 105(12):528-537 (1986). Provided asChem. Abs. AN 1987:497057 (DN 107:97057).

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