Process for the preparation of 8-halodihydrocodeinone hydrohalid

Details Process for the preparation of 8-halodihydrocodeinone hydrohalid Process for the preparation of 8-halodihydrocodeinone hydrohalid

1977-08-04

1979-02-20

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 46, C07D48902, C07D48900

Patent

active

041406877

ABSTRACT:
Compounds of the general formula ##STR1## in which X represents halogen. These compounds are useful in the production of codeinone and codeine substantially free from impurities.

REFERENCES:
patent: 2778832 (1957-01-01), Gates
patent: 3112323 (1963-11-01), Krausz
patent: 4052402 (1977-10-01), Calvo
patent: 4054566 (1977-10-01), Rapoport et al.
Gavard et al., Bull Soc. Chim France, 1965, No. 2, pp. 486-490.
Barber et al., J Med. Chem., vol. 19, No. 10, pp. 1175-1180, 10/76.

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