Process for the preparation of 7-chloro-1,2,3,4-tetrahydroquinol

Details Process for the preparation of 7-chloro-1,2,3,4-tetrahydroquinol Process for the preparation of 7-chloro-1,2,3,4-tetrahydroquinol

1982-01-15

1983-12-20

Rivers, Diana G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21522

Patent

active

044219180

ABSTRACT:
Process for the preparation of 7-chloro-1,2,3,4-tetrahydroquinolin-4-one by cyclizing 3-m-chloroanilinopropionic acid by means of an oleum, and desulphonating the resulting aromatic sulphonic acids by means of dilute sulphuric acid. The quinolinone product is useful as a starting material for the preparation of pharmaceuticals.

REFERENCES:
patent: 2558211 (1951-06-01), Elderfield et al.
patent: 3200122 (1965-08-01), Streiff
patent: 3281836 (1966-07-01), Chen
patent: 3567732 (1971-03-01), Joly et al.

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