Process for the preparation of 7.alpha.-hydroxylated steroids

Details Process for the preparation of 7.alpha.-hydroxylated steroids Process for the preparation of 7.alpha.-hydroxylated steroids

1978-09-05

1980-09-02

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435931, C12P 3306

Patent

active

042207169

ABSTRACT:
A fermentation process for the preparation of 7.alpha.-hydroxylated steroids utilizing strains of the genus Mucor is disclosed. The 7.alpha.-hydroxylated steroids are useful intermediates for the synthesis of chenodeoxycholic acid as well as steroidal hormones.

REFERENCES:
patent: 2924611 (1960-02-01), Dodson et al.
patent: 2960436 (1960-11-01), Thoma et al.
patent: 2962512 (1960-11-01), Bernstein et al.
patent: 3031477 (1962-04-01), Thoma et al.
Charney et al., Microbial Transformations of Steroids, pp. 286, 382, 383, 396, 397, 449 and 586 (1967).
Chem. Abst. 62, 7823g (1965).
J. Org. Chem. 24 286 to 289 (1959).
J. Org. Chem. 26 2856 to 2859 (1961).
Canadian J. Microbiol. 13 1271 to 1281 (1971).
Canonica et al, Gazzetta Chimica Italiana, vol. 93, pp. 301-308 (1963).

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