Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathi

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D29106

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active

045635218

ABSTRACT:
6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide is prepared by reaction of acetoacetamide with at least approximately twice the molar amount of SO.sub.3 per mole of acetoacetamide, if appropriate in an inert inorganic or organic solvent. Relevant salts can be obtained, using bases, from the product which results in the form of the acid.
The non-toxic salts, in particular the potassium salt, are valuable synthetic sweeteners.

REFERENCES:
patent: 3689485 (1972-09-01), Clauss
patent: 3969348 (1976-07-01), Pietsch et al.

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