Process for the preparation of 6-[D(-)alpha-(4-ethyl-2,3-dioxopi

Details Process for the preparation of 6-[D(-)alpha-(4-ethyl-2,3-dioxopi Process for the preparation of 6-[D(-)alpha-(4-ethyl-2,3-dioxopi

1987-10-05

1989-06-06

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Introduction of -c

540333, 544369, 548172, C07D49912, C07D41710, C07D27768

Patent

active

048373176

ABSTRACT:
The 6-[D(-)-alpha(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-alphaphenylace tamido]penicillanic acid and the salts thereof are prepared by synthetizing the novel intermediates, thioesters of D(-)-alpha-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-alpha-phenylacet ic acid, with mercaptoheterocycles and by converting them into the desired compound by reaction with 6-amino-penicillanic acid.

REFERENCES:
patent: 4610822 (1986-09-01), Boop et al.

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