Chemistry: electrical and wave energy – Processes and products
Patent
1979-05-21
1980-11-11
Edmundson, F.
Chemistry: electrical and wave energy
Processes and products
204 72, 204 78, 204 79, 204 81, 26034622, C25B 302, C25B 306, C07D30777
Patent
active
042331218
ABSTRACT:
The invention concerns a new process for the preparation of 5-halo-6,9.alpha.-oxido-prostaglandin derivatives of the general formula II ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group optionally substituted by aryl, amino, hydroxyl or a halogen atom, an equivalent of a pharmaceutically acceptable organic or inorganic cation or a conventional hydroxyl protecting group;
REFERENCES:
patent: 3427235 (1969-02-01), Le Duc
patent: 4125712 (1978-11-01), Axen
Chem. Biochem., and Pharmacological Activity of Prostanoids, Roberts et al., p. 290, pub. by Pergamon, N.Y., 1979.
Mech. of Oxidation of Org. Cpds. by Waters, pp. 49-51, pub. by Methuen, London, 1964.
Intro. to Org. Electrochem, by Rifi et al., 1974, pp. 282, 298-307, pub. by Marcel Dekker, New York.
Tamoskozi et al., Tetrahedron Letters, 1977, pp. 2627, 2628.
Kovacs nee Mindler Vera
Redey Laszlo
Szebenyi nee Gyori Eniko
Szemos nee Szonyi Agnes
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
Edmundson F.
Ross Karl F.
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