Process for the preparation of 5-fluoroanthranilic acid

Details Process for the preparation of 5-fluoroanthranilic acid Process for the preparation of 5-fluoroanthranilic acid

1994-10-06

1996-06-04

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562433, 562456, 562458, 562493, C07C 5116, C07C 51255, C07C22952, C07C 6304

Patent

active

055234720

ABSTRACT:
The present invention relates to a process for the preparation of 5-fluoroanthranilic acid, which comprises reacting 5-fluoro-2-bromotoluene in the presence of a catalyst and of an acidic solvent, with oxygen or an oxygen-containing gas at from 80.degree. to 220.degree. C., separating off the 5-fluoro-2-bromobenzoic acid formed and reacting it with ammonia at from 70.degree. to 180.degree. C.

REFERENCES:
patent: 4605757 (1986-08-01), Feld
patent: 4990659 (1991-02-01), Jihad et al.
European Search Report, Jan. 10, 1995, No. 94 11 4772.
J. Boil. Chem. Bd. 207, 1954--"Actionof some substituted Anthranilic Acids on Escheria coli ".

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