Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro

Details Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro

1980-02-19

1981-08-18

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 17R, A61K 3171, C07H 1522

Patent

active

042847648

ABSTRACT:
A novel process whereby 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols are reacted with a dialkylaminosulfur trifluoride to produce novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitol antibacterial agents.

REFERENCES:
patent: 3972930 (1976-08-01), Daum et al.
patent: 4000262 (1976-12-01), Daniels
patent: 4029883 (1977-06-01), Hiraga et al.
patent: 4065616 (1977-12-01), Umezawa et al.

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