Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1993-11-30
1995-06-20
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544229, C07D48704, C07F 718
Patent
active
054261872
ABSTRACT:
Processes for preparing 4-hydroxy-5-ethynylpyrrolo[2,3-d]pyrimidine intermediates and N-[4-(2-{4-hydroxypyrrolo[2,3-d]pyrimidin-3-yl}ethyl)benzoyl]-L-glutamic acid derivatives having antineoplastic activity are provided.
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Chauhan J.A.C.S 107, 1028 (1985).
Barnett Charles J.
Kobierski Michael E.
Berch Mark L.
Boone David E.
Conrad Robert A.
Eli Lilly and Company
Fontana Steven A.
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